Tricarboxylic acids and derivatives
Medchemexpress LLC IACS-8803 diammonium | 98.8% | 50 MG
IACS-8803 diammonium is a highly potent cyclic dinucleotide STING agonist known for its robust systemic antitumor efficacy. It has demonstrated superior antitumor activity in in-vivo studies, specifically in mice bearing bilateral B16-OVA melanomas with a 10 μg intra-tumoral injection.
- Highly potent cyclic dinucleotide STING agonist
- Robust systemic antitumor efficacy
- Molecular weight: 726.60
- Molecular formula: C20H29FN12O9P2S2
- Appearance: Solid
- Color: White to off-white
Apexbio Technology LLC Amfenac Sodium Monohydrate 61618-27-7 10mM (in 1mL DMSO)
Amfenac Sodium Monohydrate (CAS 61618-27-7) is a synthetic non-steroidal anti-inflammatory compound structurally characterized by an acetic acid moiety It functions by inhibiting cyclooxygenase (COX) enzymes consequently suppressing prostaglandin synthesis and mitigating inflammatory processes and pain signaling Amfenac Sodium Monohydrate is utilized in biomedical research to investigate inflammatory pathways and to evaluate non-steroidal analgesic drug effects in cellular and animal models of inflammation Its well-defined inhibitory mechanism makes it a valuable tool for elucidating COX-mediated physiological and pathological responses
![eMolecules 68-04-2 | Sodium citrate | Combi-Blocks | MFCD00012462 | 258.068 | C6H5Na3O7 | 98.000 | [Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 1kg | 290693721](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000129299.jpg-250.jpg)
eMolecules 68-04-2 | Sodium citrate | Combi-Blocks | MFCD00012462 | 258.068 | C6H5Na3O7 | 98.000 | [Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 1kg | 290693721
Sodium citrate | Combi-Blocks | 68-04-2 | MFCD00012462 | 258.068 | C6H5Na3O7 | 98.000 | [Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 1kg | 290693721
Medchemexpress LLC HO-PEG-CH2COOH | 95.0% | 35,000 Da | HO-(C2H4O)n-CH2COOH | 500 MG
HO-PEG-CH2COOH (MW 35,000) is a carboxy-terminated polyethylene glycol (PEG) polymer used as a hydrophilic spacer for PROTAC synthesis and other bioconjugation applications. The polymer features a hydroxyl terminus and a carboxymethyl terminus, providing a reactive carboxylic acid for coupling chemistries. Supplied as a white to off-white solid with ~95.0% purity; recommended storage is -20°C under nitrogen.
- High molecular weight PEG spacer (35,000 Da) for increased solubility and linker length.
- Carboxy-terminated for straightforward amide or ester coupling.
- Hydroxyl-terminated opposite end for orthogonal functionalization.
- Solid powder form is easy to handle and weigh for synthesis workflows.
- Stable under recommended storage; in solvent store at -80°C for extended stability.
Medchemexpress LLC Arl67156 trisodium | 1021868-83-6 | 99.9% | 785.05 g·mol-1 | C15H21Br2N5Na3O12P3 | 1 MG
ARL67156 trisodium is a small-molecule research inhibitor of ecto-ATPase (NTPDase) enzymes, provided as the trisodium salt in solid form. It is used to study nucleotide hydrolysis and related pathologies such as calcific aortic valve disease and asthma.
- Selective inhibitor of NTPDase1 (CD39), NTPDase3, and NPP1.
- Reported Ki values approximately 11 μM (NTPDase1), 18 μM (NTPDase3), and 12 μM (NPP1).
- High reported purity (99.94%).
- Molecular weight about 785.05 g·mol-1 and exact formula C15H21Br2N5Na3O12P3.
- Supplied as a solid trisodium salt, available in small research pack sizes.
- Store sealed and away from moisture at -20°C; in solution, store at -80°C (up to 6 months) or -20°C (up to 1 month).
Medchemexpress LLC DiMal-O-CH2COOH | 1620837-47-9 | 96.81% | C13H12N2O7 | 100 MG
diMal-O-CH2COOH is a cleavable ADC linker. It is for research use only and not intended for human use. This product appears as a solid with a white to off-white color.
- Cleavable ADC linker
- For research use only
- Not intended for human use
- Appears as a solid
- Color: white to off-white
- Molecular weight: 308.24
Medchemexpress LLC Magnesium citrate 100mg
Magnesium citrate (Trimagnesium dicitrate) is an orally active magnesium-containing compound that can cross the blood-brain barrier (BBB) Magnesium citrate can be used as an intestinal cleanser and is studied for its application in laxatives Magnesium citrate can also increase the pain threshold and is studied for pain-relief purposes[1][2]
Medchemexpress LLC Fmoc-NH-PEG1-CH2COOH | 260367-12-2 | 99.5% | 341.36 g/mol | C19H19NO5 | 1 G
Fmoc-NH-PEG1-CH2COOH is an Fmoc-protected PEG-based linker with a terminal carboxylic acid, designed for installation of linkers in medicinal chemistry workflows such as ADC and PROTAC synthesis.
- Used in antibody-drug conjugate linker synthesis.
- Used in proteolysis-targeting chimera (PROTAC) synthesis.
- Contains an Fmoc-protected amine and a terminal carboxylic acid for conjugation.
- White to off-white solid with good purity for research applications.
- Available in multiple sizes, including 1 g, for flexible laboratory use.
Chem-Impex International, Inc. Sodium citrate dihydrate | 6132-04-3 | MFCD00150031 | 2.5KG
Sodium citrate dihydrate, 6132-04-3, MFCD00150031, 2.5KG
Medchemexpress LLC Mosapride citrate | 112885-42-4 | 99.96% | 5 MG
Mosapride citrate is an orally active gastroenterokinetic compound, acting as a 5HT4 agonist and a CYP inducer. It demonstrates a concentration-dependent inhibitory effect on Kv4.3 with an IC50 value of 15.2 μM. This compound is suitable for use in the study of gastrointestinal diseases.
- Acts as a 5HT4 agonist
- Functions as a CYP inducer
- Exhibits concentration-dependent inhibitory effect on Kv4.3 with an IC50 of 15.2 μM
- Promotes gastric emptying
- Relieves NSAID-induced ulcers by activating the 5-HT4 receptor
Medchemexpress LLC Gefapixant citrate | 2310299-91-1 | 99.2% | 545.5 g/mol | C20H27N5O11S | 1 ML
Gefapixant citrate is a P2X3 receptor antagonist provided as a concentrated solution for laboratory research. The reagent is supplied at 10 mM in DMSO (1 mL) and is intended for in vitro pharmacology and biochemical studies, with analytical documentation available from the manufacturer.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- High purity (99.2%) suitable for research applications.
- Supports in vitro P2X3 receptor pharmacology and biochemical assays.
- Comes with data sheet, certificate of analysis, and safety data sheet.
- For research use only; not for human or diagnostic use.
Medchemexpress LLC Enclomiphene citrate | 7599-79-3 | 100.0% | 598.09 | C32H36ClNO8 | 5 MG
Enclomiphene citrate is a research-grade, non-steroidal estrogen receptor antagonist (the (E)-isomer of clomiphene) used in studies of ovarian dysfunction, testosterone deficiency, male hypogonadism, and type 2 diabetes. It is supplied as a small quantity for laboratory research and assay development.
- Research-grade estrogen receptor antagonist with antioestrogenic properties.
- Used in studies of ovarian dysfunction, hormonal regulation, and metabolic disease.
- Suitable for in vitro screening and early-stage pharmacology research.
- Compact sample size for assay development and method validation.
- Molecular formula C32H36ClNO8; molecular weight 598.09.
Crescent Chemical Co Inc TRIS-(2-CARBOXYETHYL)PHOSPHINE
Tris-(2-carboxyethyl)phosphine hydrochloride Water-soluble and odorless reagent for selective and fast reduction of disulfides. Does not react with other functional groups of proteins. Unreactive towards many common alkylating reagents, so reductions have been carried out simultaneously wit